Study finds how bacterial vaccine demonstrates potential as treatment for cancer immunotherapy – Times of India
NEW YORK: Columbia researchers developed probiotic bacteria that train the immune system to eliminate cancer cells, paving the way for a new class of cancer vaccinations that take advantage of bacteria's innate tumour-targeting abilities. These microbial cancer vaccines can be tailored to each person's specific original tumour and metastases, perhaps preventing future recurrences.In mice models of advanced colorectal cancer and melanoma, the bacterial vaccine stimulated the immune system, causing primary and metastatic malignancies to shrink - or in many cases disappear entirely. All while leaving healthy body parts alone.The findings were published in Nature.The bacterial vaccine proved to be particularly more efficacious than peptide-based therapeutic cancer vaccines that have been used ...